Internal medicine, Pharmacology and geriatric nursing 3Module Pharmacology
Academic Year 2022/2023 - Teacher: GIULIA DI BENEDETTOExpected Learning Outcomes
The course aims to allow the student to develop knowledge and skills on the pharmacological basis of the therapy through an integration of related notions: the pharmacokinetics, the mechanism of molecular action and the interaction of individual classes of drugs with the pathophysiological and molecular mechanisms of the diseases for which these drugs are proposed, as well as the methods of drug administration and the unwanted side effects.
At the end of the course the student, as far as he is competent, will be able:
- to know the pharmacological basis of the therapy;
- to know the side and toxic effects of drugs, and the potential interactions between them;
- to understand the biological reasons behind the variability of drug response.
Course Structure
Traditional
classes.
If the teaching is given in a mixed or remote mode, necessary changes may be introduced in order to fulfill all statements in the Syllabus.
Required Prerequisites
Attendance of Lessons
Detailed Course Content
The course includes two sections:
1. General pharmacology: this section describes the principles that underlie the human-drug interactions and that in turn are divided into two chapters, one related to Pharmacokinetics (the effects that the body has on drugs) and the other one on Pharmacodynamics (the cellular and molecular mechanisms that underlie the therapeutic, unwanted and toxic effects of drugs).
2. Clinical Pharmacology: this section describes the characteristics of the single classes of drugs.
Textbook Information
- Taglialatela - Conforti - Cuzzolin - Leone - Mattioli - Moretti - Pignataro – Vanzetta: Farmacologia per le lauree triennali e magistrali, III Edizione - Idelson-Gnocchi, 2021
- Amico Roxas, Caputi, Del Tacca: Compendio di Farmacologia generale e Speciale, II Edizione - EDRA, 2021
Course Planning
| Subjects | Text References | |
|---|---|---|
| 1 | General principles of Pharmacology | see textbook tab |
| 2 | Drug development | see textbook tab |
| 3 | Routes of drug administration | see textbook tab |
| 4 | Pharmacokinetics: absorption, distribution, metabolism and elimination of drugs | see textbook tab |
| 5 | Pharmacodynamics: biological targets of drugs, classification of receptors and theories, concentration-response curve | see textbook tab |
| 6 | Signal transduction mechanisms | see textbook tab |
| 7 | Adverse drug reactions | see textbook tab |
| 8 | Autonomic nervous system drugs | see textbook tab |
| 9 | Anxiolytic and hypnotic sedatives | see textbook tab |
| 10 | General and local anesthetics | see textbook tab |
| 11 | Drugs for the treatment of mood disorders | see textbook tab |
| 12 | Drugs of the cardiovascular system, blood and kidney | see textbook tab |
| 13 | Drugs acting on the respiratory system | see textbook tab |
| 14 | Diabetes mellitus medications | see textbook tab |
| 15 | Steroidal and non-steroidal antinflammatory drugs | see textbook tab |
| 16 | Drugs active on the gastrointestinal system | see textbook tab |
| 17 | General principles of chemotherapy | see textbook tab |
Learning Assessment
Learning Assessment Procedures
Examples of frequently asked questions and / or exercises
- Routes of drug administration
- Drug-receptor interactions
- Signal transduction pathways
- Drugs affecting the autonomic nervous system
- Antihypertensive drugs
- General and local anaesthetics
- Adverse drug reactions