Chemistry and biochemistry, biology and genetics 4
Module Biology and genetics

Academic Year 2022/2023 - Teacher: BARBARA TOMASELLO

Expected Learning Outcomes

The course in Biology and Genetics aims to provide a comprehensive and up-to-date knowledge of the fundamental concepts of Biology and Genetics, useful for understanding the organization and functioning of the cell, the mechanisms underlying heredity and the expression of gene information, complementing them also with references to applications so as to complete the view of the overall biological picture.

Course Structure

The course consists of face-to-face lectures. If the teaching is given in a blended or online learning mode, necessary variations from what is stated may be introduced in order to comply with the provided syllabus

Required Prerequisites

Basic knowledge of the structure and function of major biological macromolecules and the cellular metabolism

Detailed Course Content

1. Introduction to the course: the eukaryotic and prokaryotic cell;
2. Organic macromolecules: proteins;
3. Organic macromolecules: nucleic acids;
4. DNA, chromatin and chromosomes;
5. Structure and function of genes;
6. Transcription in eukaryotes and prokaryotes;
7. Translation in eukaryotes and prokaryotes;
8. DNA duplication in eukaryotes and prokaryotes;
9. Mitosis and Meiosis;
10. Point mutations and Chromosomal aberrations;
11. The Cell Membrane: structure and transport mechanisms;
12. Oncogenes, Oncosuppressors and Cancer;
13. Hints of Mendelian and human genetics.

Textbook Information

1) Biologia e Genetica. G. De Leo, S. Fasano, E. Ginelli. Ed. EdiSES (IV Edizione)

2) Fondamenti di biologia e genetica. Riccardo Pierantoni, Gilda Cobellis, Rosaria Meccariello. Ed.
EdiSES

Course Planning

 SubjectsText References
1Biological MacromoleculesText 1_chapter 1; Text 2-chapter 2
2Eukaryotic and Prokaryotic Cells Text 1_chapter 2; Text 2-chapter 3
3DNA, chromatin and chromosomes Text 2 Chapters 1 and 10
4Structure and function of genes Text 1_chapter 4; Text 2_Chapter 10
5Transcription in eukaryotes and prokaryotes Text 1_Chapter 4; text 2-chapter 5
6Translation in eukaryotes and prokaryotesText 1_ch 4; Text 2_ch 5
7DNA duplication in eukaryotes and prokaryotesText 1 Ch. 4; Text 2 Ch. 5
8Mitosis and Meiosis Text 1 Ch. 7; Text 2 Ch. 6
9Point Mutations and Chromosomal AberrationsText 1 Ch. 9; Text 2 Ch. 11
10The Cellular Membrane Text 1 ch 6; Text 2 ch 3-4
11Oncogenes, Oncosuppressants, and CancerText 1 ch 7; text 2_ ch 6
12Mendelian and human genetics Text 1 ch 10; Text 2 ch 9

Learning Assessment

Learning Assessment Procedures

Oral Examination and/or Written Examination (open and multiple choice questions).
Verification of learning may also be conducted by online tool, if the conditions should require it

Examples of frequently asked questions and / or exercises

Examples of questions and/or exercises
Gene mutations
The eucoriotic cell
The genetic code
Synthesis and maturation of mRNA
Translation
Cell membranes and transport mechanisms
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