Microbiological sciencesModule Medical Mycology
Academic Year 2022/2023 - Teacher: LAURA TROVATOExpected Learning Outcomes
The student must learn the biological and pathogenic characteristics of microrganisms that play a role in human pathology, with reference to fungi. He must acquire appropriate knowledge on the relationships between fungi and host in normal and pathological conditions, identify the transmission pathways, and know the characteristics, the activity, the mechanism of action and resistance of the main antifungal drugs. The student must also know the main methods for the cultivation and identification of a fungus. He must acquire appropriate knowledge on the principles of microbiologic laboratory methods including appropriate specimen collection.
Course Structure
Traditional lectures, with the support of slides. Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.
Detailed Course Content
- General characteristics of fungi and classification;
- Mechanisms of pathogenicity and classification of mycoses;
- Primary pathogenic fungi: dermatophytes and dimorfi t.d. and related laboratory diagnosis;
- Opportunist pathogenic fungi and related laboratory diagnostic: a) Candida, Cryptococcus, Malassezia, Pneumocystis; b) Zygomycetes, Aspergillus, Fusarium, Scedosporium;
- Subcutaneous mycosis, feoifomycosis and related laboratory diagnostic;
- Antifungal drugs: mechanism of action, resistance and tests for susceptibility in vitro.
Textbook Information
Bendinelli - Chezzi - Dettori - Manca - Morace - Polonelli – Tufano - Microbiologia Medica - Gli agenti infettivi dell' uomo: biologia, azione patogena, laboratorio- MONDUZZI EDITORE - Micologia
Course Planning
| Subjects | Text References | |
|---|---|---|
| 1 | Caratteristiche generali dei miceti e classificazione | Cap. 1 e 2 |
| 2 | Azione patogena dei miceti. Classificazione delle micosi | Cap. 2, 3, 4 e 6 |
| 3 | Miceti patogeni primari: dermatofiti e dimorfi t.d. e relativi aspetti diagnosti | Cap. 5, 9 e 11 |
| 4 | Miceti patogeni opportunisti e relativi aspetti diagnosici: Candida, Cryptococcus, Malassezia, Pneumocystis; | Cap. 5, 8, 9 e 11 |
| 5 | Miceti patogeni opportunisti e relativi aspetti diagnosici: Zigomiceti, Aspergillus, Fusarium, Scedosporium | Cap. 5, 10 e 11 |
| 6 | Micosi sottocutanee e feoifomicosi e relativi aspetti diagnostici | Cap. 5 e 9 |
| 7 | Farmaci antifungini: meccanismo d’azione, resistenza e saggi in vitro | Cap 7 |