SCIENZE MEDICO-CHIRURGICHE E FARMACOLOGICHE

Module FARMACOLOGIA GENERALE E FARMACOTOSSICOLOGIA

      

Knowledge and understanding

o   To know the principles of pharmacokinetics and pharmacodynamics, the mechanisms of action, the main indications, and the adverse reactions of commonly used drugs.

o   To understand the basics of pharmacotoxicology and the mechanisms of drug-induced toxicity, with particular attention to the biomedical context.

 

Applying knowledge and understanding

o   To apply pharmacological knowledge to interpret patients' pharmacological profiles and evaluate the impact of drugs on laboratory parameters.

o   To recognize signs of drug-induced toxicity and contribute to the analytical management of suspected intoxication or overdose cases in the biomedical laboratory setting.

 

Making judgements

o   To critically analyze clinical and laboratory data in light of the pharmacological and toxicological properties of drugs, formulating independent judgements on the compatibility of therapeutic profiles with analytical results.

o   To reflect on the ethical and professional implications of the use, abuse, and toxicity of drugs in the role of the biomedical laboratory technician.

 

Communication skills

o   To communicate clearly and correctly, both orally and in writing, information on mechanisms of action, therapeutic and toxic effects of drugs, using appropriate technical language.

o   To interact effectively with the healthcare team to support the evaluation of pharmacological and toxicological profiles in relation to laboratory results.

 

Learning skills

o   To independently update on scientific literature in the pharmacological and pharmacotoxicological field, also through databases and guidelines.

o   To develop tools for continuous learning necessary for the evolution of pharmacological therapies and analytical methods in the biomedical field.

    

Traditional classes.

If the teaching is given in a mixed or remote mode, necessary changes may be introduced in order to fulfill all statements in the Syllabus

 

·      General principles of Pharmacology

·      Routes of drug administration

·      Pharmacokinetics: absorption, distribution, metabolism, and elimination of drugs

·      Pharmacodynamics: biological targets of drugs, classification of receptors and receptor theories, concentration-response curve

·      Agonists and antagonists

·      Signal transduction mechanisms

·      Factors influencing drug response

·      Pharmacology of the autonomic nervous system

·      Pharmacology of the central nervous system

·      Drug tolerance, dependence and toxicity

·      Preclinical and Clinical Drug Testing

·      Adverse drug reactions

Karen L. Whalen: Le basi della farmacologia. Ed. Zanichelli - Quarta edizione e successive.

Clementi F. – Fumagalli G.: Farmacologia generale e molecolare. Ed. Edra - Quinta edizione e successive.

Drug administration routes

Drug metabolism

G Protein-Coupled Receptors

Pharmacovigilance