Chemistry and biochemistry, biology and genetics 2Module Chemistry and biochemistry
Academic Year 2023/2024 - Teacher: ANGELA MARIA AMORINIExpected Learning Outcomes
The Chemistry and Biochemistry course aims to provide knowledge on the structure and characterization of biological molecules, as well as the chemical-physical foundations that regulate their ability to react and transform. The study of the fundamental metabolic pathways for vital processes, based on a molecular approach, aims to direct the student to the correlation with clinical disciplines.
Course Structure
Frontal lessons
If the teaching is given in a mixed or remote way, the necessary changes may be introduced with respect to what was previously stated, in order to comply with the program envisaged and reported in the syllabus.
Information for students with disabilities and / or SLD
To guarantee equal opportunities and in compliance with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, based on the didactic objectives and specific needs.
It is also possible to contact the referent teacher CInAP (Center for Active and Participated Integration - Services for Disabilities and / or SLD) of the Department
Required Prerequisites
Detailed Course Content
Atoms, molecules; electronic models and structure of atoms, properties and periodic table of elements. Absolute and relative atomic masses, mole. The chemical bond. The solutions: concentrations, colligative properties. Basics of thermodynamics. The chemical equilibrium: properties, reaction rate, buffer systems. Electrochemistry. Characteristics of carbon compounds: classification and nomenclature (hydrocarbons, heterocyclic compounds), physical and chemical properties. Functional groups in organic chemistry: structure, characteristic reactions and biological purpose. Carbohydrates, lipids and proteins: structural and functional biochemical characteristics. Special proteins: hemoglobin and myoglobin. Enzymes: catalysis, kinetics and regulation. Bioenergetics. Carbohydrate, lipid metabolism and amino acid metabolism: main pathways and hormonal regulation. Vitamins and coenzymes.
Textbook Information
- 1.Massimo Stefani, Niccolò Taddei-Chimica & Biochimica- Zanichelli
- 2.Michele Samaja, Paroni Rita-Chimica e biochimica per le lauree triennali dell'area biomedica-Piccin 3.F. A. Bettelheim, W. H. Brown, M. K. Campbell, S. O. Farrell-Chimica e Propedeutica Biochimica- EdiSES
- 4.M. Bertoldi, D. Colombo, F. Magni, O. Marin, P. Palestini -Chimica e Biochimica- EdiSES
- 5.Siliprandi, Tettamanti-Biochimica Medica - Strutturale, metabolica e funzionale-Piccin
- 6.David L. Nelson, Michael M. Cox Lehninger Principles of Biochemistry Editor: W.H.Freeman & Co Ltd
- 7.BERG JM, TYMOCZKO JJL, STRYER L. Biochemistry Editor McMillan
- 8.VOET and VOET Biochemistry Editor Wiley
Course Planning
| Subjects | Text References | |
|---|---|---|
| 1 | La materia: atomi, molecole; modelli e struttura elettronica degli atomi, proprietà e tavola periodica degli elementi. Masse atomiche assoluta e relativa, mole. Il legame chimico. | 1,2,3,4 |
| 2 | Le soluzioni: concentrazioni, proprietà colligative. Cenni di termodinamica. L'equilibrio chimico: proprietà, velocità di reazione, sistemi tampone. | 1,2,6,8 |
| 3 | Elettrochimica. | 1,2,3,4 |
| 4 | Caratteristiche dei composti del carbonio: classificazione e nomenclatura (idrocarburi, composti eterociclici), proprietà fisiche e chimiche. | 2,4,6,7 |
| 5 | I gruppi funzionali nella chimica organica: struttura, reazioni caratteristiche e finalità biologica. | 2,4,6,7 |
| 6 | Carboidrati, lipidi e proteine: caratteristiche biochimiche strutturali e funzionali. | 5,7,8 |
| 7 | Proteine speciali: emoglobina e mioglobina. | 5,7,8 |
| 8 | Gli enzimi: catalisi, cinetica e regolazione. | 7 |
| 9 | Bioenergetica. Metabolismo glucidico, lipidico e metabolismo degli amminoacidi: vie principali e regolazione ormonale. | 5,7,8,9 |
| 10 | Vitamine e coenzimi. | 5,7,8,9 |
Learning Assessment
Learning Assessment Procedures
· Grade 29-30 with honors: The student has an in-depth knowledge of Biochemistry, can promptly and correctly integrate and critically analyze presented situations, autonomously solve complex problems, and has excellent communication skills while mastering medical-scientific language.
· Grade 26-28: The student has good knowledge of Biochemistry, can integrate and critically analyze presented situations in a linear manner, autonomously solve complex problems to some extent, and presents topics clearly using appropriate medical-scientific language.
· Grade 22-25: The student has a fair knowledge of Biochemistry, albeit limited to the main topics. They can integrate and critically analyze presented situations in a non-linear manner and present topics fairly clearly with moderate language proficiency.
· Grade 18-21: The student has minimal knowledge of Biochemistry, with limited ability to integrate and critically analyze presented situations. They present topics sufficiently clearly, although their language proficiency is not well-developed.
· Failed Examination: The student lacks the minimum required knowledge of the main course content. Their ability to use specific language is extremely limited or nonexistent, and they cannot apply acquired knowledge independently.