PATOLOGIA GENERALE E CLINICA MICROBIOLOGIA E ANATOMIA PATOLOGICA - canale 2
Academic Year 2021/2022 - 1° Year- PATOLOGIA GENERALE E CLINICA: Ferdinando Nicoletti
- Microbiology and clinical microbiology: Maria Lina Mezzatesta
- ANATOMIA PATOLOGICA: Rosario Caltabiano
Scientific field
- MED/04 - Experimental medicine and pathophysiology
- MED/07 - Microbiology and clinical microbiology
- MED/08 - Pathology
Term / Semester: 2°
ENGLISH VERSION
Learning Objectives
- PATOLOGIA GENERALE E CLINICA
The main objectives of the course will be aimed at understanding: the etiological factors responsible for the alterations of cell function; the cellular and molecular pathogenic mechanisms of pathological processes; the mechanisms underlying the responses of the body's defense and immune system disorders, in particular: hypersensitivity reactions, the immunodeficiencies and autoimmune disorders; control mechanisms of cell proliferation and apoptosis.
- Microbiology and clinical microbiology
The course aims to provide the student with the cognitive and methodological tools necessary to
understand the mechanisms of infection in the host of microorganisms and parasites; the
essential biological characteristics of the microorganisms and parasites responsible for human
infections; microorganisms in relation to the environment; infection control strategies; the
pathogenetic mechanisms of microorganisms and parasites responsible for human infections and
the methodological approach in the diagnostic assessment of infection diseases.
Course Structure
- PATOLOGIA GENERALE E CLINICA
frontal lessons
Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus
- Microbiology and clinical microbiology
- Microorganisms and parasites: Essential characteristics and differences of:
- Bacteria
- Viruses
- Fungi
- protozoa and other parasites known to infect humans.
- Host-parasite interactions and mode of infection.
- Essential concepts of microbiological diagnostics.
- Infection control
a. Sterilization, disinfection and antisepsis
b. The antimicrobial chemotherapy; importance of antibiotic-resistances
5. Essential concepts on the pathologies caused by the main pathogenic bacteria and viruses
6. Notes on infections caused by fungi and parasites
Detailed Course Content
- PATOLOGIA GENERALE E CLINICA
Environmental pathology
Cellular pathology: cellular adaptations (hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia), apoptosis, necrosis
Inflammation: acute, chronic, inflammatory mediators
Fever and alterations of the temperature
Immune system: innate immunity, acquired (cell mediated and humoral)
Hypersensitivity: I, II, III e IV type
Autoimmune disease
- Microbiology and clinical microbiology
Introduction to microbiology: types of microorganisms and the impact of microorganisms on human life.
Morphological, biochemical, physiological and genetic characteristics of:
to. bacteria
b. Virus
c. Fungi
d. Protozoa and other parasites
Relations between humans and microorganisms: symbiosis, mutualism and parasitism.
Mode of infection
Control of the infection:
a. Sterilization, disinfection and antisepsis
b. Antimicrobial chemotherapy drugs; importance of resistances
Iter of the diagnostic sample and microbiological diagnosis. Laboratory diagnosis of infectious diseases: collection and transport of pathological material; diagnosis of bacterial and viral infections
Main pathogens of infections of the oral cavity, gastrointestinal tract, respiratory tract, urogenital tract, intravasal and cardiac tract, central nervous system, skin and bone and joint; opportunistic and hospital.
Textbook Information
- PATOLOGIA GENERALE E CLINICA
Elementi di patologia ghenerale. GM Pontieri - Ed. Piccin
- Microbiology and clinical microbiology
1. Microbiologia e Microbiologia clinica per le professioni sanitarie e odontoiatria.
Autore: Simona De Grazia, Donatella Ferraro, Giovanni Giammanco. Edizione: Casa editrice: Pearson2. Microbiologia e microbiologia clinica per i corsi di laurea in professioni sanitarie, Cevenini Roberto, Piccin.
3. Quick Review, Microbiologia per le Professioni Sanitarie - D. Lembo, M. Donalisio, S. Landolfo - EdiSES.