General and clinical pathology, microbiology and pathological anatomy 1

Module General and Clinical Pathology

The course aims to provide students with a foundational knowledge of General Pathology, with particular emphasis on the etiopathogenetic mechanisms underlying disease processes. In parallel, students will acquire specific competencies in Clinical Pathology, with a focus on the critical evaluation and interpretation of the principal laboratory tests employed in the study of hematological and inflammatory disorders.

Teaching activities are delivered through frontal lectures, designed not only to convey core knowledge but also to promote critical thinking and the integration of theoretical concepts with clinical and diagnostic applications. In the event of blended or distance learning delivery, the course organization may be adapted through appropriate teaching tools and methodologies, while ensuring full alignment with the intended learning outcomes and syllabus content.

A solid understanding of the fundamentals of histology, chemistry, biochemistry, and physics is required, along with basic knowledge of general physiology of organs and systems.

Attendance is mandatory, in accordance with the requirements established by the Degree Programme regulations.

• Introduction to General Pathology 

• Concepts of homeostasis and disease 

• Physical causes of disease 

• Chemical causes of disease 

• Biological causes of disease 

• Cell pathology 

• Inflammation: classification; types of exudate; chemical mediators of inflammation; chronic inflammation and granulomas 

• Biological specimens and their handling and transport 

• Complete blood count (CBC) 

• Serum protein electrophoresis 

Le basi patologiche delle malattie (VOL.1) di V. Kumar, A.K. Abbas, J.C. Aster. Ed. EDRA

Trattato di Biochimica Clinica e Medicina di Laboratorio di M. Ciaccio, Ed. EDISES

La medicina di Laboratorio nell'Emergenza 2/ed. di G. M. Gandolfo; F. Temperilli; A. Amoroso. Ed. A. Delfino 

• Define acute inflammation (angioflogosis), highlighting the main hemodynamic and vascular changes;
• Describe the nature of granulomas, specifying their structure, function, and pathophysiological significance;
• Classify the main types of biological specimens used in clinical practice, indicating their characteristics and principal diagnostic applications;
• Define necrosis versus apoptosis, outlining their principal mechanisms and morphological features.