SCIENZE CLINICHE

Learning Objectives

• Clinical Sciences

  Students will have to describe the main mechanisms underlying cancer pathogenesis and will have to define the appropriate procedures required for the diagnosis of the most common forms of cancer. Description of currently employed techniques and their usefulness in tumor diagnosis will also be required. Finally, students will have to acquire rudimental notions concerning both conventional chemotherapeutic drugs and novel anti-tumoral biological compounds.

• Clinical Sciences - Blood Diseases I

  Learning in thre field of haematological laboratory of neoplastic and no neoplastic diseases.

• Clinical Sciences - Blood Diseases II

  Learning of the basic haemosatic laboratory and in the field of the hematological diseases and no hematologic diseases .

Course Structure

• Clinical Sciences

  Frontal Teaching and Interactive Discussion.

Detailed Course Content

• Clinical Sciences

  Tumor Biology

  • Oncogenes, Tumor Suppressor Genes
  • Stochastic Cancerogenesis and Cancer Stem Cells
  • Angiogenesis, Tumor Heterogeneity and Metastasis

   

  Epidemiology and Cancer Prevention

  · Incidence, Prevalence and Mortality Rates in Oncology

  · Risk Factors for the Most Common Tumors

  · Primary, Secondary and Tertiary Prevention

   

  Clinical Methodology in Oncology

  · Tumor Classification and Staging

  · Cancer Biomarkers

   

  Principles of Cancer Therapy

  · Conventional Chemotherapeutic Drugs

  · Hormonal Therapy

  · Targeted Therapies in Oncology

• Clinical Sciences - Blood Diseases I

  Hematopoiesis physiopathology

  Anemia Laboratory

  Lymphoproliferative and myeloproliferative diseases laboratory

• Clinical Sciences - Blood Diseases II
  • Haemostasis physiopathology
  • Coagulation physiopathology
  • Basic haemostatic laboratori (PT, PTT, Fibrinogen)
  • Specialistic haemostatic laboratory (D-Dimer, LA, PFA, Thromboelastogram)
  • Thrombocytopenia diagnostic laboratory
  • Inherited hemorrhagic disases diagnostic laboratory (haemphilia,

  von Willebrand disaese)

  • Inherited thrombophilia diagnostic laboratory
  • Acquired thrombophilia diagnostic laboratory
  • Disseminated Intravascular Coagulation (DIC) diagnostic laboratory

Textbook Information

• Clinical Sciences
  1. C. B. Thompson, J. W. Gray, J. Mendelsohn, M. A. Israel, P. M. Howley - The Molecular Basis of Cancer - 2014 - Saunders
  2. Collegio degli Oncologi Medici Italiani - Manuale di Oncologia Medica - 2018 - Edizioni Minerva Medica
• Clinical Sciences - Blood Diseases I

  1. Malattie del Sangue e dgeli Organi Emolinfopoietici - Sante Tura - Michele Baccarani, Società Editrice Esculapio

  2. Manuale di Malattie del Sangue . A. Bosi, V. De Stefano, F. Di Raimondo, G. La Nasa, Società Editrice Elsevier

  3. Ematologia Le Basi Fidsiopatologiche Molecolari e Cliniche - Giuseppe Amadori, Società Editrice Piccin

  4. Manuale di Ematologia - Paolo Corradini - Robin Foà, Società Editrice Minerva Medica

  5. Malattie del Sangue e dgeli Organi Emolinfopoietici - Gianluigi Castoldi - Vincenzo Liso, Società Editrice McGrawHill

  6. Ematologia di Mandelli - Giuseppe Avvisati, Società Editrice Piccin

• Clinical Sciences - Blood Diseases II

  1. Malattie del Sangue e degli Organi Emopolinfopoietici – Sante Tura - Michele Baccarani, Società Editrice Esculapio

   

  2. Manuale di Malattie del Sangue – A. Bosi, V. De Stefano, F. Di Raimondo, G. La Nasa, Società Editrice Elsevier

  3. Ematologia Le Basi Fisiopatologiche Molecolari e Cliniche – Giuseppe Amadori, Società Editrice Piccin

  4. Manuale di Ematologia – Paolo Corradini – Robin Foà, Società Editrice Minerva Medica

  5. Manuale di Malattie del Sangue e degli Organi Emopoietici – Gianluigi Castoldi – Vincenzo Liso, Società Editrice McGrawHill

  6. Ematologia di Mandelli – Giuseppe Avvisati, Società Editrice Piccin