SCIENZE CLINICHE

Learning Objectives

• Molecular Oncology

  Students will have to be able to describe the most important laboratory techniques currently employed for cancer diagnosis, specifying the appropriate indications to request each test and describing from a technical standpoint how each test is performed. The therapeutic implications of each test will also be discussed.

• Clinical Sciences - Blood Disesaes

  Learning in thre field of haematological laboratory of neoplastic and no neoplastic diseases.

Course Structure

• Molecular Oncology

  Lectures, seminars and interactive discussion of clinical cases.

Detailed Course Content

• Molecular Oncology

  Tumor Biology

  • Oncogenes and Tumor Suppressor Genes
  • Stochastic Cancerogenesis and Cancer Stem Cells
  • Proliferation, Angiogenesis, Tumor Heterogeneity and Metastasis

   

  Epidemiology and Cancer Prevention

  • Incidence, Prevalence and Mortality Rates in Oncology
  • Risk Factors for the Most Common Tumors
  • Primary, Secondary and Tertiary Prevention
  • Chemoprevention

   

  Clinical Methodology in Oncology

  • Tumor Classification and Staging
  • Cancer Biomarkers

   

  Principles of Cancer Therapy

  • Principles of Cancer Surgery and Radiation Therapy
  • Conventional Chemotherapeutic Drugs
  • Hormonal Therapy
  • Targeted Therapies in Oncology and Modulators of the Immune Checkpoint Blockade
• Clinical Sciences - Blood Disesaes

  Hematopoiesis physiopathology

  Anemia Laboratory

  Lymphoproliferative and myeloproliferative diseases laboratory

  Haemostatic Laboratory

Textbook Information

• Molecular Oncology
  • A. R. Bianco, S. De Placido, G. Tortora - Core Curriculum: Oncologia Clinica - 2011 - McGraw-Hill
  • R. Labianca, S. Cascinu - La Medicina Oncologica - 2013 - Edra
  • C. B. Thompson, J. W. Gray, J. Mendelsohn, M. A. Israel, P. M. Howley - The Molecular Basis of Cancer - 2014 - Saunders
• Clinical Sciences - Blood Disesaes

  1. Malattie del Sangue e dgeli Organi Emolinfopoietici - Sante Tura - Michele Baccarani, Società Editrice Esculapio

  2. Manuale di Malattie del Sangue . A. Bosi, V. De Stefano, F. Di Raimondo, G. La Nasa, Società Editrice Elsevier

  3. Ematologia Le Basi Fidsiopatologiche Molecolari e Cliniche - Giuseppe Amadori, Società Editrice Piccin

  4. Manuale di Ematologia - Paolo Corradini - Robin Foà, Società Editrice Minerva Medica

  5. Malattie del Sangue e dgeli Organi Emolinfopoietici - Gianluigi Castoldi - Vincenzo Liso, Società Editrice McGrawHill

  6. Ematologia di Mandelli - Giuseppe Avvisati, Società Editrice Piccin