PATOLOGIA GENERALE E CLINICA MICROBIOLOGIA E ANATOMIA PATOLOGICA - canale 1

Learning Objectives

• General and Clinical Pathology

  At the end of the course the student should understand the underlying causes and the pathogenetic mechanisms at the basis human diseases, as well as the etiology of the fundamental alteration of the biological structures, functions and control mechanisms. It must also know the basic biological mechanisms of defence and their alterations. The course will address the concept of pathology (or disease) from the molecular level to the upper levels of organization (cell, tissue, organ, apparatus, body).

• MICROBIOLOGIA E MICROBIOLOGIA CLINICA

  Knowledge of the basics of microbiology (general microbiology)

  Application of this knowledges to clinical cases with special regard to infectious diseases.

  Choosing the optimal pathological sample on the basis of the site of the infection and of the suspected diagnosis; evaluation of the best systems for the collection, transportation and storage of pathological samples

  Deep knolwledge of prevention, prophylaxis, diagnosis and diagnostic methods, treatments and eventual emergency procedures in infectious diseases.

• Anatomic Pathology

  At the end of course the student will be able to distinguish the type of cyto-histopathological samples and to adopt correctly the appropriate conservation techniques;

  use an appropriate language, but understandable, demonstrating to have learned the elementary notions related to the alterations of organs and tissues, not neoplastic and neoplastic.

Course Structure

• General and Clinical Pathology

  Lectures in the classroom with the teacher

• MICROBIOLOGIA E MICROBIOLOGIA CLINICA

  Lectures in the classroom with the teacher.

• Anatomic Pathology

  Frontal teaching

Detailed Course Content

• General and Clinical Pathology
  • Introduction to the General Pathology
  • Genetic Diseases
  • Environmental Pathology
  • Cellular Pathology: cellular adaptations (hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia), apoptosis, necrosis
  • Inflammation: acute, chronic, inflammatory mediators
  • Regeneration, repair and healing
  • Fever and temperature changes
  • Immune system: innate, acquired immunity (cell mediated and humoral)
  • Hypersensitivity: I, II, III and IV type
  • Tumors
• MICROBIOLOGIA E MICROBIOLOGIA CLINICA

  Introduction to the microbial world: bacteria, fungi, protozoa, viruses

  Overview of the structure, metabolism, reproduction and replication models of microorganisms.

  Principles of the treatment of the infections

  Routes of infection and host response characteristics; prevention of the infection.

  Collection of pathological samples based on the site of infection, characteristics of the treated germs, diagnostic methods available.

  Pathology, pathogenesis, diagnostic systems.

  Application of the notions transmitted to simulated clinical cases

• Anatomic Pathology

  Elements of histocitopathological technique

  Histopathological examinations: incisional and excisional biopsies, surgical biopsy, cytological examinations. Examples

  Preservation of biological samples: chemical and physical fixation; intraoperative histological examination. Examples

  General Pathological Anatomy

   

  Non-neoplastic alterations: hypertrophy, hyperplasia, atrophy, hypotrophy, aplasia, metaplasia; examples

  Non-neoplastic cellular necrosis: meaning, particular types; apoptosis; examples

  Neoplasms: general characters: dysplasia, carcinoma in situ, invasive carcinoma; examples

  Benign and malignant, epithelial and non-epithelial tumors: classification; examples

  Grade and stage of neoplasia: examples

Textbook Information

• General and Clinical Pathology

  Elementi di patologia generale per corsi di laurea in professioni sanitarie, Giovanni M. Pontieri – Piccin

  Patologia Generale – Maurizio Parola - EdiSES

• MICROBIOLOGIA E MICROBIOLOGIA CLINICA
  1. Antonelli, Clementi, Pozzi, Rossolini : Principi di Microbiologia medica – Ed. Ambrosiana

  2. La Placa : Principi di Microbiologia Medica – Ed. Esculapio

  3. Jawetz, Melnick, Adelberg’s: Microbiologia medica – Ed. Piccin
  4. Sherris: Microbiologia Clinica, Ed. EMSI
  5. Murray et al.: Microbiologia Clinica - Ed. Elsevier
• Anatomic Pathology

  Anatomia Patologica- Le basi- Luigi Ruco, Aldo Scarpa. Edizioni UTET